Photoinduced Transcription by Using Temporarily Mismatched Caged Oligonucleotides

Abstract

Spatial and temporal control of the function of DNA with light: In oligonucleotides, protected (“caged”) thymidine can act as a temporary mismatch in base pairing and, for example, prevent transcription. The photolabile caging group can be removed by light (see picture), fully restoring an intact DNA strand. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z461779_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.