The Journal of Laryngology & Otology · 2008 · 29 citations · 11 references
DentistryOral SurgeryOral Tissue RegenerationOral Wound HealingReconstructive Oral SurgeryLaser ResurfacingLaser SurgeryKtp Laser TreatmentSubmucous FibroidsWilcoxon Signed-rank Test
INTRODUCTION: Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. Various treatment modalities are available for its management, but these have largely been ineffective. MATERIALS AND METHODS: Nine cases of oral submucous fibrosis underwent a release procedure using a KTP-532 laser, from March 2005 to January 2006, within the ENT-head and neck surgery department of a tertiary centre. RESULTS: Pre- and post-operative mouth-opening was compared using the Wilcoxon signed rank test, and a significant difference observed (Z = -2.690, p = 0.007). Follow up over an average period of 12 months showed encouraging results. CONCLUSION: This preliminary study indicated that adequate release of oral submucous fibrosis can be achieved by using a KTP-532 laser release procedure, with minimal morbidity and satisfactory results. These promising results should encourage more widespread use of this technique in the management of this condition.
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Oral submucous fibrosis: its pathogenesis and management
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Stimulation of human buccal mucosa fibroblasts in vitro by betel-nut alkaloids
W. Harvey, Andrew Scutt, S Meghji et al. · Archives of Oral Biology · 1986 · 198 citations