Concepedia

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

Clay C. C. Wang, Yi‐Ming Chiang, Shu‐Chiao Sung, Ya‐Ling Hsu, Jiunn‐Kae Chang, Po‐Lin Kuo

Cancer Letters · 2007 · 201 citations · 32 references

DOI

Concepts

References

32

Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium

Victoria H. Freedman · Cell · 1974 · 813 citations

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Reactive oxygen species in tumorigenesis.

Daniel I. Feig, Thomas M. Reid, Lawrence A. Loeb · PubMed · 1994 · 476 citations

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Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells

Yi‐He Ling, Leonard Liebes, Yiyu Zou et al. · Journal of Biological Chemistry · 2003 · 461 citations · Full text

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Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.

Qing‐Bai She, Ann M. Bode, Nan Yue Chen et al. · PubMed · 2001 · 393 citations

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Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-κB Activation and NF-κB-regulated Gene Products Through Modulation of p65 and IκBα Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents

Santosh K. Sandur, Haruyo Ichikawa, Gautam Sethi et al. · Journal of Biological Chemistry · 2006 · 320 citations · Full text

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