Herniated Intervertebral Disc-Associated Periradicular Fibrosis and Vascular Abnormalities Occur Without Inflammatory Cell Infiltration

Abstract

The vascular abnormalities detected in patients may represent an important etiopathologic factor predisposing to intraneural and perineural fibrosis, and hence to chronic pain symptoms, after disc herniation. It seems important to preserve the perineural microcirculation following disc herniation.