Low CD4 Count Is Associated With an Increased Risk of Fragility Fracture in HIV-Infected Patients

Abstract

This is the largest clinical study to date of fragility fractures occurring in an HIV-infected population. The study found that risk of fracture was strongly associated with a low CD4 cell count, use of corticosteroids, and anti-epileptic medications. There were no associations between fracture risk and viral load, use of class, or duration of antiretroviral agent.