Journal of the American Academy of Audiology · 2005 · 15 citations · 29 references
Health ProfessionsAudiologyNeuroscienceAuditory ElectrophysiologyHearing SciencePsychophysiologyAuditory Evoked PotentialsAuditory NeurophysiologyAuditory PhysiologyAuditory ThresholdsHearing ImpairmentHearing LossAuditory Late ResponsesBehavioral Hearing ThresholdsLate-latency Auditory Evoked PotentialsN1-p2 ComplexOddball ParadigmPsychoacoustic ThresholdsSupra-threshold Response AnalysisSuprathreshold Perception
Psychophysical and P300 (P3) thresholds and suprathreshold measures were obtained in 16 normal-hearing subjects. Subjects followed a classic oddball paradigm using 1000 (frequent) and 2000 Hz (rare) tones as stimuli. The P3 was obtained for all 16 subjects at or 5 dB above their behavioral threshold. The P3 was obtained more often at behavioral threshold and 5 dB SL than N1 and P2 late potentials. The P3 was larger in amplitude than either the N1 or the P2 at threshold and for 75 dB SPL stimuli. In comparing P3s obtained at threshold and for the 75 dB stimuli, significant effects were noted in latency and amplitude reflecting exogenous aspects to this endogenous potential. Differences in latency and amplitude were also noted in N1 and P2 waveforms obtained from the rare versus frequent stimuli. Clinical implications of these results are discussed. Se obtuvieron mediciones psicofísicas así como umbrales y mediciones supraumbrales de la onda P300 (P3) en 16 sujetos normo-oyentes. Los sujetos siguieron un paradigma clásico y peculiar utilizando como estímulo tonos de 1000 Hz (frecuente) y de 2000 Hz (infrecuente). La P3 se obtuvo para los 16 sujetos a nivel de umbral conductual o a 5 dB por encima de éste. La P3 se obtuvo más a menudo a nivel de umbral conductual y a 5 dB SL, que los potenciales tardíos N1 y P2. La P3 fue mayor en amplitud que la N1 o la P2 a nivel umbral, y para estímulos de 75 dB SPL. Al comparar las P3 obtenidas a nivel umbral y con estímulos de 75 dB, se notaron efectos significativos en latencia y amplitud, que reflejaban aspectos exógenos de este potencial endógeno. Se notaron también diferencias en latencia y amplitud en las formas de onda N1 y P2 obtenidas de estímulos infrecuentes versus frecuentes. Se discuten las implicaciones clínicas de estos resultados.
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Contributions of temporal-parietal junction to the human auditory P3
Robert T. Knight, Donatella Scabini, David L. Woods et al. · Brain Research · 1989 · 512 citations
Task-dependent field potentials in human hippocampal formation
Gregory McCarthy, C. C. Wood, PD Williamson et al. · Journal of Neuroscience · 1989 · 266 citations · Full text