Organic Letters · 2011 · 295 citations · 34 references
Natural SciencesChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisAlkylation ProcessesAlkylation ReactionsHeterocycle FunctionalizationHeterocyclic Materials
A direct alkylation of various heteroaryls using stoichiometric potassium alkyl- and alkoxymethyltrifluoroborates has been developed. This method leads to the synthesis of complex substituted heterocycles, which have been obtained with yields up to 89%.
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