Concepedia

ETB receptor antagonist, IRL 1038, selectively inhibits the endothelin-induced endothelium-dependent vascular relaxation

Hideaki Karaki, Sri Agus Sudjarwo, Masatoshi Hori, Kiyoshi Sakata, Yoshihiro Urade, Michihiro Takai, Toshikazu Okada

European Journal of Pharmacology · 1993 · 48 citations · 11 references

DOI

Concepts

References

11

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

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Cloning and expression of a cDNA encoding an endothelin receptor

Hiroshi Arai, Seiji Hori, Ichiro Aramori et al. · Nature · 1990 · 2.6K citations

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The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

Akiko Inoue, Masashi Yanagisawa, Sadao Kimura et al. · Proceedings of the National Academy of Sciences · 1989 · 2.5K citations · Full text

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Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

Takeshi Sakurai, Masashi Yanagisawa, Yoh Takuwat et al. · Nature · 1990 · 2.4K citations · Full text

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Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Gilberto De Nucci, Ranjeny Thomas, Pedro D’Orléans-Juste et al. · Proceedings of the National Academy of Sciences · 1988 · 1.4K citations · Full text

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