Journal of Heterocyclic Chemistry · 2001 · 21 citations · 10 references
Natural SciencesChemistryMedicinal ChemistryGreen ChemistryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisSafer Chemical SynthesisPurificationVacuum Distillation
Abstract This study represents a facile synthesis of building blocks ( 1–3 ) of crown ethers and amine precoursers ( 4a‐d ). The study also involves synthesis of mono and dibenzo N, N ‐disubstituted diaza 18‐crown‐6 derivatives with high yield without chromatographic purification and high vacuum distillation. The complex ability of host the ethers was evaluated in terms of structural modification.
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Principles and Synthetic Applications in Crown Ether Chemistry
George W. Gokel, H. D. Durst · Synthesis · 1976 · 201 citations
Chiral recognition in complexation of guests by designed host molecules
D. J. CRAM, Roger C. Helgeson, Lynn R. Sousa et al. · Pure and Applied Chemistry · 1975 · 118 citations · Full text