Prolactin induces the production of Th17 and Th1 cytokines/chemokines in murine Imiquimod‐induced psoriasiform skin

Abstract

These results suggest that intraperitoneal PRL enhances the expression of Th17 and Th1 cytokines/chemokines, and augments inflammation in imiquimod-induced psoriasiform skin. Prolactin may thus exacerbate psoriasis through the enhancement of Th17/Th1 responses.