Bronchodilator Response in Relation to β2-Adrenoceptor Haplotype in Patients with Asthma

Abstract

Genetic variation of the ADRB2 does not influence the immediate response to inhaled beta2-agonist. The confounding effect of tolerance resulting from regular beta2-agonist use must be controlled when assessing the pharmacogenetic influences on clinical outcomes with beta2-agonists.