Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

Marina R. Picciotto, Michèle Zoli, Roberto Rimondini et al. · Nature · 1998 · 1.3K citations

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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

Robert Freedman, Hilary Coon, Marina Myles‐Worsley et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations

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Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

Robert Freedman, Michael E. Hall, Lawrence E. Adler et al. · Biological Psychiatry · 1995 · 679 citations

Life Sciences, Neurobiology, Neuroscience +11

On the reaction of cells and of nerve‐endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari

J. N. Langley · The Journal of Physiology · 1905 · 595 citations

Life Sciences, Pharmacology, Physiology +10

Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

Avi Orr‐Urtreger, Finn M. Göldner, Mayuko Saeki et al. · Journal of Neuroscience · 1997 · 499 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17