Microsurgery · 2005 · 107 citations · 8 references
MedicinePlastic SurgerySurgeryMicrosurgeryPeripheral Nerve SurgeryReconstructive SurgeryFacial Nerve SurgeryNerve GraftingNerve ReconstructionNerve RegenerationNerve RepairNeural RegenerationCranial Nerve LesionsFacial Nerve OriginNerve Defect ReconstructionNerve Gap ReconstructionNerve Graft ReconstructionNerve Regeneration AssessmentPolyglycolic AcidSurgical Nerve Repair
Facial nerve reconstruction for lesions with nerve gaps frequently require autologous or tubulized grafts of biological or synthetic origin. Neurotube, a bioabsorbable polyglycolic acid tube, represents a valid solution for this kind of defect in emergency and planned surgery. Seven posttraumatic lesions of terminal branches of the facial nerve were repaired by means of Neurotube from September 1999-September 2001. The nerve gap size ranged between 1-3 cm. Nerve regeneration was evaluated at 7-12 months of follow-up when muscle recovery function was examined. Muscle function was very good in 1 case, good in 4, and fair in 2 (71% positive results). No intolerance or discomfort was reported or observed. Neurotube is useful for the reconstruction of facial nerve lesions with a small nerve gap (less then 3 cm) when a direct anastomosis of the two stumps is not possible, or when the suture appears to be in tension. It is a valid alternative to autologous and biological tubulized grafts. The limits of this method are: 1) it can only be used with gaps of less than 3 cm; 2) it is quite costly; 3) there are reports of possible intolerance; and 4) it is not suitable for lesions of the proximal part of the facial nerve.
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Surgery of the peripheral nerve
Danielle Harrison · British Journal of Plastic Surgery · 1989 · 811 citations
Medicine, Neurosurgery, Surgery +11
Bridging nerve defects with combined skeletal muscle and vein conduits
Giorgio Brunelli, Giorgio Brunelli, Bruno Battiston et al. · Microsurgery · 1993 · 157 citations
Medicine, Neurosurgery, Surgery +16