Receptor reserve at striatal dopamine autoreceptors: Implications for selectivity of dopamine agonists

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Sigmoidal Dose-response Curves, Physiologically-based Pharmacokinetic Modeling, Bioanalysis +21

COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS*

Robert F. Furchgott, Paula Bursztyn · Annals of the New York Academy of Sciences · 1967 · 527 citations

Neurophysiology, Medicine, Functional Selectivity +7

Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis.

Michael J. Bannon, Richard L. Michaud, Robert H. Roth · PubMed · 1981 · 193 citations

Da Antagonist Haloperidol, Synaptic Transmission, Neurotransmitter +21

Characterization of dopamine autoreceptor and [3H]spiperone binding sites in vitro with classical and novel dopamine receptor agonists

John Lehmann, Michael S. Briley, S Z Langer · European Journal of Pharmacology · 1983 · 132 citations

Functional Selectivity, Medicine, Neurotransmitter +9

Inactivation of D1 and D2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: selective protection by neuroleptics.

Emanuel Meller, Karen Bohmaker, Menek Goldstein et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 131 citations