Association of<i>NLRP1</i>genetic variants and mRNA overexpression with generalized vitiligo and disease activity in a Gujarat population

Abstract

Our results suggest that NLRP1 rs2670660 and rs6502867 polymorphisms may be genetic risk factors for susceptibility to and progression of GV. The upregulation of NLRP1 mRNA in patients with susceptible genotypes advocates the crucial role of NLRP1 in GV.