IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

A.M. James Shapiro, Jonathan R.T. Lakey, Edmond A. Ryan et al. · New England Journal of Medicine · 2000 · 5.3K citations · Full text

Medicine, Endocrinology, Surgery +16

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

Nucleic Acids Research · 2002 · 3.5K citations · Full text

Life Sciences, Biostatistics, Molecular Biology +15

Variance stabilization applied to microarray data calibration and to the quantification of differential expression

Wolfgang Huber, Anja von Heydebreck, Holger Sültmann et al. · Bioinformatics · 2002 · 2.6K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +13

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

Michio Kawano, Toshio Hirano, Tadashi Matsuda et al. · Nature · 1988 · 1.7K citations

Medicine, Immunology, Oncology +11

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

Shigeomi Shimizu, Yutaka Eguchi, Hiroaki Kosaka et al. · Nature · 1995 · 614 citations

Life Sciences, Cell Biology, Molecular Medicine +10