Exogenous L-Arginine Protects Liver Microcirculation from Ischemia Reperfusion Injury

Abstract

These data indicate that L-arginine improves hepatic microcirculation after warm ischemia by increasing sinusoidal perfusion rate and by diminishing leukocyte endothelium interactions. Maintained integrity of microcirculation is associated with sufficient oxygen supply and improved hepatocellular function.