The Anal Fistula Plug Treatment Compared With the Mucosal Advancement Flap for Cryptoglandular High Transsphincteric Perianal Fistula: A Double-Blinded Multicenter Randomized Trial

Abstract

The results of the anal fistula plug and advancement flap procedures are disappointing in the multicenter setting. There were no significant differences in recurrence, functional outcome, and quality of life between the plug and the advancement flap. Because the plug is simple to apply and minimally invasive, it can be considered as an initial treatment option for high transsphincteric fistulas.