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THE FACILE SYNTHESIS OF LACTONES
228
Citations
7
References
1976
Year
Abstract Direct LactonizationEngineeringω-Hydroxy AcidsOrganic ChemistryCatalysisChemistrySynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringGood Yields
Abstract Direct lactonization of ω-hydroxy acids, HO(CH22)nCOOH with n=5, 7, 10, 11, 14, has been successfully carried out under mild conditions in good yields by the treatment with 1-methyl-2-chloropyridinium iodide in the presence of triethylamine. In the case of the acid with n=6, only lactide has been produced.
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