Urinary excretion of 8-hydroxy-2′-deoxyguanosine measured by high-performance liquid chromatography with electrochemical detection

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry · 1992 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

César G. Fraga, Mark K. Shigenaga, J W Park et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

Mark K. Shigenaga, Carlos J. Gimeno, B N Ames · Proceedings of the National Academy of Sciences · 1989 · 735 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index

Steffen Loft, Kirsten Vistisen, Marianne Ewertz et al. · Carcinogenesis · 1992 · 643 citations

Medicine, Oncology, Carcinogenesis +10

A rapid gas-liquid chromatographic method for the determination of cotinine and nicotine in biological fluids

C Feyerabend, Michael A. Russell · Journal of Pharmacy and Pharmacology · 1990 · 312 citations

Pharmacy, Toxicology, Analytical Chemistry +9