Clinical Nuclear Medicine · 2014 · 12 citations · 12 references
MedicineOncologyRadiologyDiagnostic RadiologyMetastasisNeoplasiaParathyroid CancerParathyroid NeoplasmsThyroid CancerThyroid ImagingTumor CharacterizationTumor ImagingBrown TumorsLytic Bone LesionsNeoplastic DiseaseParathyroid Lesion CytologyParathyroid PathologyParathyroid Tumor DiagnosisParathyroid Tumor ImagingRadiotracer Uptake Quantification
A 29-year-old female patient exhibited a solitary neck mass, severe hypercalcemia, and multiple skeletal lytic lesions consistent with metastatic neoplastic disease. Fine-needle aspiration (FNA) cytology of the neck lesion indicated a follicular thyroid neoplasm. CT-guided bone biopsy was non-diagnostic. Subsequent 18F-FDG PET/CT examination demonstrated avid glucose uptake within the neck mass and diffuse bony lesions of variable metabolic activity. Repeat biopsy utilizing PET/CT guidance produced core tissue with classic histologic features of a brown tumor. Postoperative histology revealed an exclusively oncocytic parathyroid adenoma. Atypical radiotracer uptake of this rare functioning adenoma subtype is illustrated with discussion of improved procedural diagnostic yield utilizing PET/CT.
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FDG PET of Primary Benign and Malignant Bone Tumors: Standardized Uptake Value in 52 Lesions
Jun Aoki, Hideomi Watanabe, Tetsuya Shinozaki et al. · Radiology · 2001 · 318 citations
Medicine, Nuclear Medicine, Oncology +17
Comparison of FDG-PET and sestamibi-SPECT in primary hyperparathyroidism.
Donald R. Neumann, Caldwell B. Esselstyn, Raymundo T. Go et al. · PubMed · 1996 · 106 citations