Concepedia

Evaluation of a New Molecular Test, the BD Max Cdiff, for Detection of Toxigenic Clostridium difficile in Fecal Samples

Rémi Le Guern, Stéphanie Herwegh, Bruno Grandbastien, René Courcol

Journal of Clinical Microbiology · 2012 · 33 citations · 10 references

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Abstract

A new molecular assay detecting toxigenic Clostridium difficile, the BD Max Cdiff (Becton, Dickinson), was evaluated with 360 diarrheal feces samples. It exhibited high sensitivity (97.7%) and specificity (99.7%). The positive (97.7%) and negative (99.7%) predictive values of this test allow an accurate answer within 2 h.

References

10

Comparison of Nine Commercially Available <i>Clostridium difficile</i> Toxin Detection Assays, a Real-Time PCR Assay for <i>C</i> . <i>difficile tcdB</i> , and a Glutamate Dehydrogenase Detection Assay to Cytotoxin Testing and Cytotoxigenic Culture Methods

K. Eastwood, Patrick Else, André Charlett et al. · Journal of Clinical Microbiology · 2009 · 332 citations · Full text

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Rapid Detection of <i>Clostridium difficile</i> in Feces by Real-Time PCR

Simon Bélanger, Maurice Boissinot, Natalie Clairoux et al. · Journal of Clinical Microbiology · 2003 · 219 citations · Full text

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Impact of Strain Type on Detection of Toxigenic <i>Clostridium difficile:</i> Comparison of Molecular Diagnostic and Enzyme Immunoassay Approaches

Fred C. Tenover, Susan Novak-Weekley, Christopher W. Woods et al. · Journal of Clinical Microbiology · 2010 · 204 citations · Full text

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Point-Counterpoint: What Is the Current Role of Algorithmic Approaches for Diagnosis of <i>Clostridium difficile</i> Infection?

Mark H Wilcox, Tim Planche, Ferric C. Fang et al. · Journal of Clinical Microbiology · 2010 · 105 citations

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Simplified procedure for the routine isolation of Clostridium difficile from faeces.

S. P. Borriello, Pauline Honour · Journal of Clinical Pathology · 1981 · 97 citations · Full text

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