The heterotetrameric architecture of the epithelial sodium channel (ENaC)

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Cecilia M. Canessa, Laurent Schild, Gary Buell et al. · Nature · 1994 · 2K citations

Natural Sciences, Biochemistry, Biophysics +13

A proton-gated cation channel involved in acid-sensing

Rainer Waldmann, Guy Champigny, Frédéric Bassilana et al. · Nature · 1997 · 1.3K citations

Natural Sciences, Biochemistry, Biophysics +12

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

Richard A. Shimkets, David G. Warnock, Christopher M. Bositis et al. · Cell · 1994 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +15

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs

Emily R. Liman, Jan Tytgat, Peter Hess · Neuron · 1992 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +15

Determination of the subunit stoichiometry of a voltage-activated potassium channel

Roderick MacKinnon · Nature · 1991 · 929 citations

Natural Sciences, Biochemistry, Biophysics +13