Redox Report · 2006 · 23 citations · 17 references
Veterinary MedicinePharmacologyToxicologyEcotoxicologyEnvironmental ToxicologyPesticide ToxicologyInsecticide ToxicityInsecticide ToxicologyMechanisms Of Pesticide ToxicityPesticide EcotoxicologyPesticide ExposureRespiratory Toxicity Of PesticidesLung Function DeclineLung Function TestingOxidative Stress In Toxicant ExposureOxidative Stress In ToxicityOxidative Stress InjuryPesticide Exposure EffectsPesticide-induced Oxidative StressReduced Glutathione
The study was conducted to assess the magnitude of oxidative stress and lung function abnormalities in 34 male pesticide sprayers on exposure to pesticides in mango plantations. Biochemical studies on blood antioxidant enzymes revealed an unchanged glutathione level and increased level of malondialdehyde (P < 0.001), which indicates that pesticide sprayers may have suffered from oxidative stress. Decreased acetyl-cholinesterase levels (P < 0.001) in sprayers compared to the controls suggest inhibition of cholinesterase activity. The present study shows that pesticide toxicity might lead to oxidative stress and airway narrowing resulting in decreased peak expiratory flow rate.
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Environmental and Economic Costs of Pesticide Use
David Pimentel, H. Acquay, M. Biltonen et al. · BioScience · 1992 · 771 citations