Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs

Regional blood flow measurement with pulsed Doppler flowmeter in conscious rat

Joseph R. Haywood, Richard A. Shaffer, C. Fastenow et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1981 · 362 citations

Engineering, Biomedical Engineering, Physiology +17

Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent.

Pancras C. Wong, William A. Price, Andrew T. Chiu et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 330 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2).

Pancras C. Wong, S D Hart, Alverna M. Zaspel et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 294 citations

Medicine, Endocrinology, Pharmacology +17

The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives

John V. Duncia, Andrew T. Chiu, David J. Carini et al. · Journal of Medicinal Chemistry · 1990 · 241 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Nonpeptide angiotensin II receptor antagonists. Studies with EXP9270 and DuP 753.

Pancras C. Wong, William A. Price, Andrew T. Chiu et al. · Hypertension · 1990 · 131 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +11