Concepedia

Organocatalytic Asymmetric Transfer Hydrogenation of Nitroolefins

Nolwenn J. A. Martin, Lidia Ozores, Benjamin List

Journal of the American Chemical Society · 2007 · 204 citations · 18 references

DOI

Concepts

Abstract

We describe a highly efficient and highly enantioselective Hantzsch ester mediated conjugate transfer hydrogenation of β,β-disubstituted nitroolefins that is catalyzed by a Jacobsen-type thiourea catalyst.

References

18

Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts

Tomotaka Okino, Yasutaka Hoashi, Yoshiji Takemoto · Journal of the American Chemical Society · 2003 · 1.4K citations

, , +4

Organocatalysis Mediated by (Thio)urea Derivatives

Stephen J. Connon · Chemistry - A European Journal · 2006 · 839 citations

, , +17

Urea‐ and Thiourea‐Substituted Cinchona Alkaloid Derivatives as Highly Efficient Bifunctional Organocatalysts for the Asymmetric Addition of Malonate to Nitroalkenes: Inversion of Configuration at C9 Dramatically Improves Catalyst Performance.

Séamus H. McCooey, Stephen J. Connon · Angewandte Chemie International Edition · 2005 · 660 citations

, , +8

Highly Enantioselective Catalytic Acyl-Pictet−Spengler Reactions

Mark S. Taylor, Eric N. Jacobsen · Journal of the American Chemical Society · 2004 · 601 citations

, , +7

Structure-Based Analysis and Optimization of a Highly Enantioselective Catalyst for the Strecker Reaction

Petr Váchal, Eric N. Jacobsen · Journal of the American Chemical Society · 2002 · 571 citations

, , +17