Serum Levels of Soluble Tumor Necrosis Factor Receptors and Effects of Interferon Therapy in Patients With Chronic Hepatitis C Virus Infection

Abstract

The TNF alpha-TNFRs system, especially the TNFR p75-mediated pathway, is involved in the hepatic inflammation-fibrosis process in chronic hepatitis C. The serum levels of sTNFR p75, but not sTNFR p55, were correlated with the serum levels of macrophage colony stimulating factor in this process.