The nucleotide pool is a significant target for oxidative stress

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

César G. Fraga, Mark K. Shigenaga, J W Park et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

Mark K. Shigenaga, Carlos J. Gimeno, B N Ames · Proceedings of the National Academy of Sciences · 1989 · 735 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Long-Distance Charge Transport in DNA:  The Hopping Mechanism

Bernd Giese · Accounts of Chemical Research · 2000 · 652 citations

Life Sciences, Biochemistry, Molecular Biology +9

Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model.

Shinya Toyokuni, Tomoyuki Tanaka, Yuki Hattori et al. · PubMed · 1997 · 584 citations

Medicine, Cancer Biology, Oncology +8