Lymphocyte and Immature Dendritic Cell Infiltrates in Differentiated, Poorly Differentiated, and Undifferentiated Thyroid Carcinoma

Clara Ugolini, Fulvio Basolo, Agnese Proietti, Paolo Vitti, Rossella Elisei, Paolo Miccoli, Antonio Toniolo

Thyroid · 2007 · 89 citations · 10 references

Abstract

Though a relationship between the extent of lymphocyte/DC infiltrates and the prognosis of PTCs could not be demonstrated, tumors with poor prognosis (PDCs, UCs) were characterized by markedly reduced lymphocyte/DC infiltrates. The study appears to confirm the protective role of DC and infiltrating lymphocytes against thyroid tumors.

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