Seizure Disorders in Autism

Fred R. Volkmar, Douglas S. Nelson

Journal of the American Academy of Child & Adolescent Psychiatry · 1990 · 441 citations · 11 references

Concepts

TL;DR

Autistic individuals are reported to have an increased risk of seizure disorders, especially during adolescence. The study examined seizure frequency in 192 autistic individuals, finding that 21% had a seizure disorder. Among the cohort, 21% had seizures, with higher prevalence in those with lower IQ, a 3‑ to 22‑fold age‑specific risk relative to the general population, and the greatest risk occurring in early childhood but remaining elevated into early adolescence.

Abstract

Several reports have suggested that autistic individuals are at greater risk for developing seizure disorders, particularly in adolescence. In this study the frequency of seizures in a series of 192 autistic individuals was examined; 21% of cases had exhibited a seizure disorder. Seizure disorders were more common among individuals with lower IQ. Age specific incidence revealed a 3− to 22-fold increase in risk for seizure relative to the normal population. In contrast to previous studies, risk for developing seizures was highest during early childhood although it was also elevated during early adolescence. Several reports have suggested that autistic individuals are at greater risk for developing seizure disorders, particularly in adolescence. In this study the frequency of seizures in a series of 192 autistic individuals was examined; 21% of cases had exhibited a seizure disorder. Seizure disorders were more common among individuals with lower IQ. Age specific incidence revealed a 3− to 22-fold increase in risk for seizure relative to the normal population. In contrast to previous studies, risk for developing seizures was highest during early childhood although it was also elevated during early adolescence.

References

11