Helvetica Chimica Acta · 1969 · 23 citations · 13 references
Life SciencesBiochemistryEnzymologyMetabolismReactive Oxygen SpeciesCalcium AtpaseCardiac Glycosides
Abstract The synthesis of the hitherto unknown 14‐ epi ‐digitoxigenin ( 8 ) and of 3‐deoxy‐digitoxigenin ( 16 ) is described. The 15,15‐propylene‐thio‐sulfoxides 6 and 7 proved to be valuable intermediates. The results of the cardiotonic activity (ATPase test) of the cardenolides 8 and 16 are reported.
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George I. Poos, Glen E. Arth, Roger E. Beyler et al. · Journal of the American Chemical Society · 1953 · 486 citations