Assessment of protein expression and gene status of human epidermal growth factor receptor (<scp>HER</scp>) family molecules in ameloblastomas

Abstract

Expression of HER family molecules, especially EGFR and HER4, in odontogenic tissues suggests that growth signals mediated by these receptor molecules contribute to cell proliferation, survival, and differentiation in both normal and neoplastic odontogenic epithelial tissues. Some of these molecules might be useful for predicting outcomes in patients with ameloblastomas.