Concepedia

Characterization of an adaptive immune response in microsatellite-instable colorectal cancer

Florence Boissière‐Michot, Gwendal Lazennec, Hélène Frugier, Marta Jarlier, Lise Roca, Jacqueline Duffour, Emilie Du Paty, Daniel Laune, France Blanchard, Florence Le Pessot,

OncoImmunology · 2014 · 90 citations · 52 references

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Concepts

Abstract

T cells. Our findings highlight the major role of adaptive immunity in MSI CRC and provide a possible explanation for the more favorable prognosis of this CRC subtype.

References

52

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

Jérôme Galon, Anne Costes, Fátima Sánchez‐Cabo et al. · Science · 2006 · 6.5K citations

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Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer

Franck Pagès, Anne Berger, Matthieu Camus et al. · New England Journal of Medicine · 2005 · 2.1K citations · Full text

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Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

Daniel J. Sargent, Silvia Marsoni, Geneviève Monges et al. · Journal of Clinical Oncology · 2010 · 1.6K citations · Full text

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Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

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Tumor-Infiltrating FOXP3 <sup>+</sup> T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

Paul Salama, Michael Phillips, Fabienne Grieu et al. · Journal of Clinical Oncology · 2008 · 975 citations

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