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Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B

Guinea PigsFunctional SelectivityMedicinePhysiologyImmunologyReceptor (Biochemistry)PharmacotherapySimultaneous BlockadePharmacology5-Ht1a/b Receptors