(±)‐5′‐Nor ribofuranoside carbocyclic guanosine

Abstract

Abstract The synthesis of the guanine derivative (±)‐2‐amino‐1,9‐dihydro‐9‐[(1′α,2′β,3′β,4′α)‐(2′,3′,4′‐trihydroxy‐1′‐cyclopentyl]‐6 H ‐purin‐6‐one ( 2 ) is described. This compound is viewed as the carbocyclic ribofuranoside guanine nucleoside analogue lacking the 5′‐methylene.