Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis

Abstract

Serum VEGF levels are increased in systemic sclerosis patients with sPAP >or= 35 mmHg. The correlation between VEGF levels and systolic pulmonary artery pressure may suggest a possible role of VEGF in the pathogenesis of PAH in systemic sclerosis.