Ophthalmic surgery, lasers & imaging retina · 2010 · 19 citations · 21 references
Health ProfessionsOphthalmologyVision ScienceBiomedical OpticsOcular DiseaseOcular ImagingMacular DiseaseMacular DisordersMacular ImagingOptical Coherence TomographyRetinal DisordersRetinal ImagingMacular Disease AssessmentMacular Optical Coherence TomographyMacular Thickness MeasurementRetinal Disease AssessmentRetinal Layer ThicknessRetinal Thickness AnalysisSpectral-domain Optical Coherence TomographyTime-domain Optical Coherence Tomography
BACKGROUND AND OBJECTIVE: To evaluate and compare the intra-session repeatability of retinal thickness measurements from the Topcon 3D OCT 1000 (Topcon Medical Systems; Paramus, NJ), a spectral-domain optical coherence tomography (SD-OCT) system, with the Stratus (Carl Zeiss Meditec, Inc., Dublin, CA), a time-domain OCT (TD-OCT) system, in eyes with retinal diseases. PATIENTS AND METHODS: Repeated scans with both SD-OCT and TD-OCT were taken. Thickness measurements from high-quality scans were used to assess repeatability and compare measurements between the two instruments. RESULTS: Paired scans from 127 eyes were evaluated, of which 63 pairs were of high quality. Coefficients of repeatability and variation for the central subfield were 20.1 μm (2.6%) with SD-OCT and 27.4 μm (4%) with TD-OCT (P = .38). The mean difference in central subfield thickness between the two instruments was 24.5 μm (standard deviation = 20.9). CONCLUSION: Repeatability of retinal thickness measurements with the Topcon 3D OCT 1000 is comparable to the Stratus. The measurements of the two machines differ significantly and cannot be used interchangeably.
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A H BECKETT, M ROWLAND, P TURNER · The Lancet · 1965 · 16.9K citations
Anne E. Fung, Geeta A. Lalwani, Philip J. Rosenfeld et al. · American Journal of Ophthalmology · 2007 · 972 citations