Changes in plasma Angiotensin II with noise exposure and their relationship to TTS

Abstract

Plasma concentrations of the vasoconstrictor Angiotensin II (AII) were measured in male human subjects before and after either rest or exposure to 100-dB white noise. Plasma AII concentrations decreased for subjects in the control (no noise) condition but remained high in the noise condition. In the noise exposure condition both the pre- and post-exposure AII concentrations were negatively but nonsignificantly correlated with TTS. The cardiovascular effects of noise appear to be mediated in part by AII.