Pesticide Science · 1978 · 76 citations · 21 references
Life SciencesEntomologyNeuroscienceInsect NeurobiologyInsect PhysiologyNeuropharmacologyCockroach BiologyInsect Nervous System AnatomyInsecticide ToxicityNeurotoxic InsecticidesNeurotoxicity In WildlifePeripheral Nervous SystemCentral Nervous System EffectsCockroach NeurobiologyCockroach PhysiologyInsecticide NeurotoxicityIntraneural ElectrodesPeripheral Nervous System DisordersPeripheral Nervous System PharmacologyTopical Application
Abstract The action of allethrin has been studied in the free‐walking cockroach, Periplaneta americana (L) using implanted electrodes, at 15 and 32°C, following topical application of an LD 95 dose (that at 32°C being approximately ten times the LD 95 at 15°C). At both temperatures there was marked hyperexcitation of the peripheral nervous system. At 32°C there was also hyperexcitation of the central nervous system but central effects at 15°C were probably secondary. Likewise, nerve blockage often did not occur until many hours after paralysis and could thus be a secondary consequence of allethrin poisoning.
21
Mode of action of pyrethroids.
Toshio Narahashi · PubMed · 1971 · 181 citations · Full text
Medicine, Neuroscience, Pharmacology +16