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Non-classical antifolates. Part 2: Synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones

Medicinal ChemistryMolecular Modeling StudyBioorganic ChemistryBiochemistryNatural SciencesMedicineNew 2,6-Substituted-quinazolin-4-onesOrganic ChemistryNon-classical AntifolatesHeterocycle ChemistryPharmacologyDerivative (Chemistry)Drug Discovery