Overt Irritability/Anger in Unipolar Major Depressive Episodes

Lewis L. Judd, Pamela J. Schettler, William Coryell, Hagop S. Akiskal, Jess G. Fiedorowicz

JAMA Psychiatry · 2013 · 190 citations · 29 references

Abstract

This study extends results of cross-sectional investigations and indicates that irritability/anger during MDEs is a highly prevalent clinical marker of a more severe, chronic, and complex depressive illness. Findings have important implications for assessment and treatment.

References

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