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Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition

Conserved Disulfide BondSignal TransductionAdenosine A2a ReceptorBiochemistryG Protein-coupled ReceptorLigand-binding RecognitionMedicineFunctional SelectivityReceptor (Biochemistry)Non-peptide LigandPharmacologyCell BiologyCell SignalingCellular Physiology