Reduction by Fentanyl of the Cp50Values of Propofol and Hemodynamic Responses to Various Noxious Stimuli

Abstract

The authors successfully defined the propofol concentration required for various stimuli. Tracheal intubation was the strongest stimulus. The absence of somatic reactions for propofol does not guarantee hemodynamic stability without fentanyl. Propofol with fentanyl was able to suppress motor and hemodynamic reactions to various noxious stimuli.