Concepedia

A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation

Sang‐Hee Lee, Youngpyo Nam, Ja Young Koo, Donghyun Lim, Jongmin Park, Jiyeon Ock, Jaehong Kim, Kyoungho Suk, Seung Bum Park

Nature Chemical Biology · 2014 · 132 citations · 15 references

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15

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.2K citations

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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

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Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

Tiziana Bonaldi · The EMBO Journal · 2003 · 1.2K citations · Full text

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Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Huan Yang, Mahendar Ochani, Jianhua Li et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

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Microglia and neuroinflammation: a pathological perspective.

Wolfgang J. Streit, Robert E. Mrak, W. Sue T. Griffin · Journal of Neuroinflammation · 2004 · 1K citations · Full text

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