Preparation, Characterization of CeO₂-ZrO₂Composite Hollow Microspheres and Their Application as Electrocatalysis Materials for Hemoglobin in Biosensor

Abstract

Composite hollow microspheres of CeO2-ZrO2 were prepared by using anionic PSA latex particles as template and then calcining the PSA core particles at 600°C. The samples were characterized by XRD, TEM, TG, SEM, EDS, and FT-IR spectra. The effects of the proportion of CeO2 on the structure of the microspheres were also studied. Electrochemical assay showed that the CeO2-ZrO2 composite hollow spheres hydrided with chitosan could be used as a novel biosensing material to detect the direct electron transfer of hemoglobin.