Concepedia

β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis

Jing Liu, Ye Zhang, Jinglei Qu, Ling Xu, Kezuo Hou, Jingdong Zhang, Xiujuan Qu, Yunpeng Liu

BMC Cancer · 2011 · 136 citations · 27 references

DOIFull text

Open access

Abstract

Our data provides the first evidence that β-elemene induces protective autophagy and prevents human gastric cancer cells from undergoing apoptosis. A combination of β-elemene with autophagy inhibitor might thus be a useful therapeutic option for advanced gastric cancer.

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