Recurrent Aseptic Meningitis Due to Sulindac

Abstract

Brief Reports1 September 1983Recurrent Aseptic Meningitis Due to SulindacC. FORDHAM VON REYN, M.D.C. FORDHAM VON REYN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-3-343 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAseptic meningitis previously has been seen after administration of sulindac, tolmetin, and ibuprofen only in patients with systemic lupus erythematosus or mixed connective tissue disease (1-8). This report describes a case of recurrent aseptic meningitis caused by sulindac in a woman without demonstrable systemic rheumatic disease.First Episode: A 72-year-old woman with hypertension, hypothyroidism, and pernicious anemia was given sulindac for osteoarthritis of the knees. Four months later, in December 1979, she was hospitalized with fever and headache. Her spinal fluid was clear with the leukocyte count, 245/mm3(89% polymorphonuclear cells, 11% mononuclear cells); protein, 88 mg/dL; and glucose, 56...References1. BALLASDONTA ZS. Sulindac-induced aseptic meningitis. Arch Intern Med. 1982;142:165-6. CrossrefMedlineGoogle Scholar2. RUPPERTBARTH GW. Tolmetin-induced aseptic meningitis. JAMA. 1981;245:67-8. CrossrefMedlineGoogle Scholar3. BERNSTEIN R. Ibuprofen-related meningitis in mixed connective tissue disease. Ann Intern Med. 1980;92:206-7. LinkGoogle Scholar4. WIDENERLITTMAN HB. Ibuprofen-induced meningitis in systemic lupus erythematosus. JAMA. 1978;239:1062-4. CrossrefMedlineGoogle Scholar5. RUPPERTBARTH GW. Ibuprofen hypersensitivity in systemic lupus erythematosus. South Med J. 1981;74:241-3. CrossrefMedlineGoogle Scholar6. GIANSIRACUSABLUMBERGKANTROWITZ DSF. Aseptic meningitis associated with ibuprofen [Letter.] Arch Intern Med. 1980;140:1553. Google Scholar7. SAMUELSONWILLIAMS CH. Ibuprofen-associated aseptic meningitis in systemic lupus erythematosus. West J Med. 1979;131:57-9. MedlineGoogle Scholar8. WASNER C. Ibuprofen, meningitis, and systemic lupus erythematosus. J Rheumatol. 1978;5:162-4. MedlineGoogle Scholar9. JOHNSONRICHARDSON RE. The neurological manifestations of systemic lupus erythematosus: a clinical-pathological study of 24 cases and review of the literature. Med. 1968;47:337-69. CrossrefMedlineGoogle Scholar10. BENNETTBONGSPARGO RDB. Neuropsychiatric problems in mixed connective tissue disease. Am J Med. 1978;65:955-62. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Concord Hospital Concord, New Hampshire PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDrug-induced aseptic meningitisDrug-Induced Aseptic MeningitisIbuprofen-Induced Aseptic Meningitis in Rheumatoid ArthritisDrug-induced meningitisSPossible Optic Nerve Side Effeects Associated with Nonsteroidal Anti-Inflammatory DrugsDrug- and Chemical-Induced Aseptic Meningitis: A Review of the LiteratureRheumatic DisordersOther Connective Tissue Disorders and The Use of GlucocorticoidsDrug-induced aseptic meningitisNaproxen-Induced Recurrent Aseptic MeningitisThe Acute Aseptic Meningitis SyndromeNoninfectious Causes of Acute CNS InflammationRecurrent Encephalitis due to Trimethoprim IntakeTrimethoprim-sulfamethoxazole-associated aseptic meningitis: Case reports and review of the literatureResident Article: Ibuprofen-Associated Meningitisin a Woman with Only Serologic Evidence of a Rheumatologic DisorderAseptic Meningitis Associated with NaproxenTreatmentSide‐effects of non‐steroidal anti‐inflammatory drugsPhenazopyridine and Aseptic MeningitisTIMOTHY E. HERLIHY, M.D.Clinical pharmacology of non-steroidal anti-inflammatory drugsTrimethoprim Associated Aseptic MeningitisIbuprofen and Aseptic MeningitisDANIEL L. BOULAND, M.D., N. LENNARD SPECHT, M.D., DOUGLAS R. HEGSTAD, M.D.Disorders that Mimic CNS InfectionsReferencesAnti-inflammatory analgesics and drugs used in rheumatoid arthritis and goutLes méningites chroniques: un carrefour à baliser analyse de 5 observations et revue de la littératureIbuprofen and MeningoencephalitisDAVID R. PERERA, M.D., A. KURT SEIFFERT, M.D., H. MCLEAN GREELEY, M.D. 1 September 1983Volume 99, Issue 3Page: 343-344KeywordsCellsInfectious diseasesKneesLupus erythematosusMeningitisMixed connective tissue diseaseOsteoarthritisPernicious anemiaProteinsSystemic diseases Issue Published: 1 September 1983 PDF downloadLoading ...