Abstract

Aureomycin. injected intraperitoneally starting 24 hours after intranasal infection of cotton rats with the virus of primary atypical pneumonia almost completely inhibits the development of pulmonary consolidation when given in daily doses of 1 mg, and is partly active at a dosage of 0.5 mg per day. Therapeutic activity with doses of 2.0 to 5.0 mg daily was also demonstrable when the beginning of treatment was delayed for 5 to 6 days.