Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer’s, Parkinson’s, and other neurodegenerative diseases

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A. Cherny, Craig Atwood, Michel Xilinas et al. · Neuron · 2001 · 1.5K citations · Full text

Life Sciences, Neuroscience, Pharmacology +13

Structural aspects of antioxidant activity of flavonoids

S.A.B.E. van Acker, Dirk‐Jan van den Berg, Michèl N. J. L. Tromp et al. · Free Radical Biology and Medicine · 1996 · 1.3K citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

Elizabeth Jones-Villeneuve, Michael W. McBurney, Kem A. Rogers et al. · The Journal of Cell Biology · 1982 · 795 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +10

Spin trapping. Kinetics of the reaction of superoxide and hydroxyl radicals with nitrones

Eli Finkelstein, Gerald M. Rosen, Elmer J. Rauckman · Journal of the American Chemical Society · 1980 · 652 citations

Natural Sciences, Biochemistry, Chemistry +10

Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo

Deepinder Kaur, Ferda Yantiri, Subramanian Rajagopalan et al. · Neuron · 2003 · 619 citations · Full text

Life Sciences, Neuroscience, Pharmacology +10