Journal of the American Chemical Society · 2011 · 273 citations · 65 references
Natural SciencesChemistryCatalysisOrganic ChemistryOrganometallic ChemistryCoordination ChemistryCross-coupling ReactionsMetal Ion CatalysisMigratory InsertionC - C Coupling ReactionsCarbene Insertion ReactionsCopper-catalyzed CouplingCross-coupling CatalysisStereoselective Cross-couplingTransition-metal-catalyzed Cross-coupling
Cu-catalyzed cross-coupling of N-tosylhydrazones with 1,3-azoles leads to the direct C-H benzylation or allylation. Cu carbene migratory insertion is proposed to play the key role in this transformation.
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